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A truly interdisciplinary collaboration between biology, law and neuroscience at Vanderbilt University has used functional magnetic resonance imaging fMRI to watch how the brain changes when a person thinks about crime and punishment.

An effective method for in vivo detection of early therapeutic response of patients with non-Hodgkin's lymphoma would enable personalized clinical management of cancer therapy and facilitate the design of optimal treatment regimens. This study evaluates the feasibility of <I>T</I><sub>2</sub>-weighted MRI and diffusion-weighted MRI for <I>in vivo</I> detection of response of human diffuse large B-cell lymphoma xenografts in severe combined immunodeficient mice to chemotherapy.

Researchers in the US and France may have overturned decades of theory in magnetic resonance studies by spotting a discrepancy in the way nuclear spins behave. Their new mathematical model of the process improves our understanding of atomic behaviour and could lead to better NMR spectra, sharper magnetic resonance images, and perhaps one day a fully portable MRI machine.

This special issue of NBM, guest edited by Bruce Berkowitz from Wayne State University School of Medicine in Detroit, focuses on MRI studies of retinal and optic nerve physiology as reviewed by leaders in the field.

Functional magnetic resonance imaging studies reveal that voters are persuaded more by the negative aspects of a politician's looks than by the positive features. The findings apply specifically if the voter was previously unaware of the politician. Ahead of the US elections, voters there should read on but let their political conscience guide their voting decision.

There is a pressing need for retina-specific imaging biomarkers that robustly measure early changes in physiology, are linked to the histopathology responsible for vision loss, and, importantly, predict treatment efficacy. In this paper, the authors conclude that functional MRI biomarkers are most promising for prognostic evaluation of treatment efficacy earlier in the course of retinopathy than is currently possible.

Functional magnetic resonance imaging (fMRI) has revealed a reason why the excitement of unwrapping presents dwindles as our brains get older and more jaded. According to a new study, a biochemical pathway is responsible for mellowing our expectations.

1H MRS has great potential for the clinical investigation of childhood brain tumours, but the low incidence in, and difficulties of performing trials on, children have hampered progress in this area.

Magnetic resonance imaging could provide an early diagnosis of osteoarthritis (OA), the most common form of arthritis, according to scientists speaking at the recent meeting of the American Chemical Society.

NMR-visible mobile lipids are important biomarkers in the diagnosis of brain tumours and monitoring the effects of treatment response.

A new MRI technique has been developed to allow physicists to see deep within tiny magnets. The technique could improve our understanding of magnetism at the fundamental level and lead to better computer hard drives and perhaps even new small-scale MRI instruments.

The purpose of this study was to measure cerebral metabolites in brains of human immunodeficiency virus (HIV)-infected patients using 2D 1H-MRS, which enables more sensitive detection of metabolites at lower concentrations and delineation of the components of the different choline groups in the frequency domain when compared to 1D 1H-MRS.

Not everything is black and white, perhaps with the exception of MRI. Aside from the artificial colours that can be added by computer, MRI is a technique of contrasts and greyscales. However, that could all change soon thanks to the ongoing development of microscopic magnetic particles by researchers in the US who hope to bring a little colour to MRI.

In this paper, the authors assessed 1H-MRS as a screening tool for detection of hippocampal sclerosis in patients with temporal lobe epilepsy.

MRI breast scans are associated with more mastectomies. That is the conclusion from a study by Mayo Clinic researchers in the USA. They have found that after an earlier, seven-year decline, there has been a sharp rise in the number of whole-breast mastectomies.

The purpose of this research was to study the changes in limb blood flow during lower extremity exercise using phase contrast MRI in normal volunteers.

US researchers have used MRI studies to demonstrate that a form of rehabilitation therapy for treating the effects of stroke causes the brain to repair itself.

A new fast and accurate tissue typing technique has recently been successfully applied to prostate MR spectroscopic imaging data. This technique is based on canonical correlation analysis, a statistical method able to simultaneously exploit the spectral and spatial information characterizing the MRSI data.

US researchers have used functional magnetic resonance imaging (fMRI) for the first time to monitor how the brain copes with disgust while watching video nasties. They found that the grin and bear it approach does not work nearly so well as positive reappraisal of the images one is seeing.

NMR-based metabonomic analysis is a well-established approach to characterizing healthy and diseased states. The aim of this study was to investigate inter-individual variability in the metabolic urinary profile of a healthy population, not subjected to strict dietary limitations, by NMR-based metabonomics.