Detectors
Potential of atmospheric pressure chemical ionization source in GC-QTOF MS for pesticide residue analysis British and Spanish scientists have tested the potential of using atmospheric pressure chemical ionization with gas chromatography-mass spectrometry to identify pesticides in foodstuffs such as spinach.
Metal microbes Utilising a newly-developed chromatography technique that employs two different forms of mass spectrometry, US scientists have found that metal-containing proteins are much more varied and widespread than previously suspected.
The use of CE with contactless conductivity detection for monitoring of glycerol in adipose tissues during a sporting performance Czech scientists have developed a CE procedure employing capacitively coupled contactless conductivity detection for determining glycerol and mannitol polyalcohols in biological and pharmacological samples.
Determination of fluoroquinolone antibiotics in wastewater using ultra HPLC with mass spectrometry and fluorescence detection Utilising both mass spectrometry and fluorescence detection, a team of Czech scientists has developed a new HPLC method for determining five fluoroquinolones in wastewaters.
Size is no laughing matter What do you do when the size difference between a chromatography column and a mass spectrometer becomes too great? You replace the column with a differential mobility spectrometer.
Multi-residue method for the analysis of pharmaceutical compounds in sewage sludge, compost and sediments Spanish chemists have developed an HPLC method that employs both diode array and fluorescence detectors for simultaneously determining 16 pharmaceutical compounds in sewage sludge, compost and sediment.
Advances and analytical applications in chemiluminescence coupled to capillary electrophoresis This review presents the recent developments, key strategies and analytical applications of chemiluminescence detection coupled to capillary electrophoresis.
The many faces of starch Modified corn starch is used in everything from pizzas to washing powder, but only by utilising field flow fractionation and light scattering detection are scientists now able to discover exactly how the starch is modified.
Strong anion-exchange liquid chromatography coupled with isotope ratio mass spectrometry using a Liquiface interface British scientists have tested the performance of a commercially-available interface known as Liquiface in coupling strong anion exchange chromatography with isotope ratio mass spectrometry.
Determination of serum cholestanol by semi-micro HPLC with electrochemical detection Using electrochemical detection, Japanese scientists have developed a simple and sensitive method for determining cholestanol, an important breakdown product of cholesterol, that does not require derivatization.
All that glitters Not only does glittering gold produce attractive jewellery, but it can also detect numerous disease biomarkers simultaneously, say Dutch scientists.
Efforts to improve detection sensitivity for CE coupled to atmospheric pressure photoionization MS Swedish scientists have discovered that coupling atmospheric pressure photoionization mass spectrometry to capillary electrophoresis allows use of a wider range of separation buffers without compromising detection sensitivity.
Evaluation of a dual-wavelength size exclusion HPLC method with improved sensitivity to detect protein aggregates US scientists have developed a dual-wavelength UV detector for use with HPLC and shown that it can detect protein aggregates in antibody formulations, as can be generated by elevated temperatures and intense light during storage.
Dance of the light brigade Not only can optical fibers conduct gas chromatography but they can also monitor analytes as they separate, say Canadian physicists.
Generation of gold nanostructures at the surface of platinum electrode by electrodeposition for ECL detection for CE By depositing gold nanostructures on the surface of a platinum electrode, Chinese scientists have developed a novel, sensitive electrochemiluminescence detection method for capillary electrophoresis.
Determination of curcumol in rat plasma by capillary gas chromatography with a hydrogen flame ionization detector Using a hydrogen flame ionization detector, Chinese scientists have developed a simple and sensitive capillary gas chromatography method for determining curcumol in rat plasma.
Who turned out the lights? For a sensitive detection method, rather than utilising chemiluminescence to make analytes fluoresce against a dark background, make the dark analytes stand out against a fluorescent background, say Chinese and US chemists.
Optimization of a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins By optimising a known derivatization agent, a European team of scientists has developed a GC/MS method for glycerol enrichment that measures the intact glycerol backbone and is suitable for electron ionization.
The use of <i>in vitro</i> technologies coupled with high resolution accurate mass LC-MS for studying drug metabolism in equine drug surveillance Using liquid chromatography combined with two high resolution mass spectrometers, British scientists have studied the phase I metabolism of eight drugs of relevance to drug surveillance in horse racing.
Follow the paper trail Brazilian scientists have developed a way to couple amperometric detection with paper chromatography, producing a cheap but sensitive analytical system for detecting biomolecules, potentially including disease biomarkers.