Detectors
Hydrophobicity-aided potentiometric detection of catecholamines, beta-agonists, and beta-blockers in a CE system An international team of scientists has shown that a series of cationic drug-like substances, including 13 beta-blockers, can be detected in a capillary electrophoresis system using a novel potentiometric sensor.
The detector that wasn't there What kind of detector is best suited for detecting analytes at the small scales found on capillary electrophoresis microchips? For two US scientists, the answer is no detector at all.
Accelerator mass spectrometry of small biological samples Swedish researchers have managed to apply accelerator mass spectrometry, an ultra-sensitive technique for isotopic ratio measurements, to the routine analysis of small biological samples.
Simultaneous LIF and retro-reflected beam interference detection for CE Chinese scientists have developed a novel optical detection method for capillary electrophoresis, based on a combination of laser-induced fluorescence detection and retro-reflected beam interference detection.
The sound of smuggling By developing a highly sensitive detector based on a phenomenon known as surface acoustic waves, US scientists have come up with a portable gas chromatograph device for detecting contraband in cargo containers.
Mass spectrometry in biodefense This review looks at the way that mass spectrometry is being used to identify potential bioagents, including microorganisms and toxins, by analysing proteins, peptides and other biomarkers.
Isotope ratio mass spectrometry coupled to liquid and gas chromatography for wine ethanol characterization By coupling isotope ratio mass spectrometry with both high-performance liquid chromatography and gas chromatography, Spanish researchers have developed two new procedures for determining carbon isotope ratios in wine ethanol.
Island spotting British scientists have developed the first new method for identifying proteins in over 20 years, which they hope can lead to a novel protein detector for use with liquid chromatography and capillary electrophoresis.
Determination of pharmaceuticals classified as emerging pollutants using CE with capacitively coupled contactless conductivity detection Using capillary electrophoresis with capacitively coupled contactless conductivity detection, scientists from Switzerland and Singapore have simultaneously separated 13 pharmaceutical products that are emerging pollutants in water.
Speciation of manganese binding to biomolecules in pine nuts Spanish chemists have brought together a range of chromatographic detection techniques including ultraviolet detection, inductively coupled plasma MS and electrospray ionization MS for determining manganese in pine nuts.
Metal catches the light By showing that a novel LED-based detection system can sensitively detect various metals, Irish scientists have opened up the possibility of developing a miniaturised version of high performance chelation ion chromatography.
Method for the analysis of more than 140 pesticide residues in fruits and vegetables by GC coupled to triple quadrupole MS Spanish analytical chemists have developed a new multiresidue method for determining more than 140 pesticide residues in cucumber and orange by gas chromatography coupled to triple quadrupole mass spectrometry.
Improvements for the visualization of low-molecular weight protein and peptides of human tears using MALDI Australian researchers have used MALDI-TOF mass spectrometry in conjunction with a number of different sample preparation techniques, including liquid chromatography, to analyse the potentially bioactive proteins in human tears.
Worth its weight in gold Three physicists from the University of California at Berkeley have constructed the smallest and most sensitive mass spectrometer ever and shown that it is able to measure the mass of a single gold atom.
Evaluation of the coupling between UPLC and evaporative light scattering detector for selected phytochemical applications Swiss and Italian chemists have assessed the benefits of coupling an ultra performance liquid chromatography column to an evaporative light scattering detector, in terms of efficiency and sensitivity, compared with a UV detector.
Introduction of HPLC/orbitrap mass spectrometry as screening method for doping control Russian scientists have developed a new method for detecting doping agents in athletes' urine, based on HPLC and an orbitrap mass spectrometer with in-source collision-induced dissociation and atmospheric pressure chemical ionisation.
Double detection is elementary Chinese chemists have not only managed to fit two different detectors onto one tiny capillary electrophoresis microchip, but have also arranged them so that they can detect the same analytes at exactly the same time.
Highly sensitive double-fluorescent dye staining on microchip electrophoresis for analysis of milk proteins Japanese scientists have developed a highly sensitive double-fluorescent dye staining method for analysing proteins by microchip electrophoresis and shown that it can detect milk proteins at levels as low as 200pg.
Investigation of interaction between human hemoglobin and anticancer drugs by CIEF with whole column imaging detection Canadian scientists have used capillary isoelectric focusing with whole column imaging detection to investigate the interaction of platinum-based anticancer drugs, including cisplatin, with human hemoglobin.
Good vibrations US engineers have shown that their newly developed mass measurement device, based on a vibrating silicon strip, should make an ideal universal detector for microchip-based separation systems.